The reason for the QuEChERS matrix effect in the liquid state is generally considered to be due to the non-volatile components in the matrix and the substance to be tested, which competes in the ionization process.
The matrix effect in gas phase temperament is generally attributed to the decomposition of the thermally unstable target due to matrix involvement during transport of the target through the hot inlet to the column; or because the matrix shields the active site of the inlet Thus, the polar target is reduced by the active site.
Then, for foods with more complex ingredients, the matrix that affects the recovery rate includes lipids, proteins, and pigments, sugars, organic acids, and salts.
Remove matrix
The amino functional group of the PSA adsorbent can react with some acidic groups to remove polar organic acids, as well as some sugars and lipids. C18EC is a porous adsorbent that can be used for non-polar physical adsorption. Removal of lipids and sterols; GCB (graphitized carbon) has a good adsorption effect on chlorophyll and its polar small interfering substances. It is important to emphasize that GCB is very easy to adsorb the target of planar structure; It is a new type of polymer with special selectivity for fat.
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