Described as a “quick-and-dirty” method in literature, flash chromatography is a method of liquid chromatographic separation in the chemical and organic laboratories, especially when you seek for fast preparative applications. flash chromatography can be carried out with hands or with the appropriate equipment.
Flash column chromatography has become a common tool when separating fine chemicals since its description in the 1970s. Different from HPLC, in process of the flash chromatography, compounds will be separated on normal phases under low pressure. Therefore, flash chromatography is called as low-pressure or medium-pressure liquid chromatography.
If you compare flash chromatography with HPLC separation, you will find the flash chromatography more efficient and economical, in the way of saving both of your time and money. Different from HPLC, in process of the flash chromatography, compounds will be separated on normal phases under low pressure. Therefore, flash chromatography is called as low-pressure or medium-pressure liquid chromatography.
A flash chromatography system is perfect for precisely analyzing the separation peak by using a UV or IR detector. Due to the modular design, the flash column chromatography systems can be reconfigured too.
Twenty years ago, the first packed flash chromatography columns were marked as the big progress in the field of flash chromatography. Today, the legend is still helping us a whole new level of improving the quality and efficiency of the process of isolating a single chemical compound from mixed samples.
Packed with C8 reversed phase silica, Hawach C8 columns have an excellent resolution for critical separations. Compared with C18 columns, they can not only provide faster analysis but increase selectivity and reproducing ability as well. Hawach C8 columns which need marginally more polar phase than C18, have a high surface area. That factor can provide additional resolution to the polar phase.
As a kind of less hydrophobic column with high surface area, optimal carbon load, and unique bonded silica packing, Hawach C8 column is an ideal choice when analytical laboratories need extra selectivity and higher speed than the C18 column. These columns also can provide you the stable and reliable results with a long using-life, high silica gel quality, worldwide Luer fittings, and lowest cost for your lab.
Distribution Balance of Flash Column
Hawach flash column is a distribution method based on distribution balance. The chromatographic system consists of two phases, one is the stationary phase and the other is the mobile phase. When the two phases move relative, the difference in the distribution equilibrium properties of each component in the mixture is repeatedly used, and finally, the purpose of separating each other is achieved.
Chromatography has been invented for more than 80 years. It is a common method for purifying and separating organic or inorganic substances. The stationary phase polarity is larger than the mobile phase, and the opposite is reverse phase chromatography.
The activity of Adsorbent and Its Regulation
The adsorption capacity of adsorbents is often called activity. The adsorbent activity depends on how much of their water content and the most active adsorbent contains the least amount of water. The activity of adsorbent is generally divided into five levels, expressed by I、II、III、IV and V, respectively. The larger the number IS, the smaller the activity IS. Adding certain water to the adsorbent can reduce its activity; conversely, if some water in the adsorbent is removed by heating treatment, it can increase its activity, which is called the activation of the adsorbent.
Hawach C8 Flash Columns, Always Ready For Your Separation Requirements
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