Columns Ahead Statement
Generally speaking, SPE/FLASH is mainly applied to the pretreatment of samples.
People can easily perceive that SPE/FLASH columns separate salt and sugar, while HPLC ones can make glucose, maltose and sucrose apart from the sugar solution, which posses more similar properties to each other than salt and sugar do. Hence, the HPLC column requires higher power of stationary phases and separating with a corresponding higher prices.
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