2019年12月18日星期三

How Do You Choose And Maintain The Syringe Filter?

Syringe filters can be used in HPLC analysis and IC analysis to filter the sample solution, which is an important step in sample preparation. As the main component of the syringe system pollution control, it is important to understand the classification and selection of the syringe filter. Different types of membranes with different pore sizes can filter mobile phases and samples to clarify bacteria and remove impurities. It is important to protect the chromatographic system and column.
Choice of syringe filter
1. Casing: High-pressure polypropylene (PP) is resistant to high temperatures, does not leak, does not require membrane replacement and cleaning, and saves complicated and time-consuming preparation work. It is a filter for HPLC and GC small sample.
2. Selection of filter specifications: Φ13μm and Φ25μm are commonly used, that is, Φ13μm is used for 2-10ml sample size, and Φ25μm is used for 10-100ml sample size.
The structure design of the syringe filter is precise, which ensures smooth filtering, rationalized internal space, and very low residual rate. It is widely used in pharmaceutical analysis, food testing, environmental monitoring, protein removal and sterility testing.
Compatible and Incompatible Substance
Hawach syringe filter can be used in numerous filtration situations, including corrosive and non-corrosive mobile phases based on solvents. To select a qualified product is significant, the non-conforming product is dissolved in the impurity, and the solvent to be filtered is soaked for 24 hours to see whether the dissolved phenomenon exists. There are some suggestions on reducing wrong operation in experiment. It is reasonable to reduce salt variables and avoid particle coalescence of columns and meters. It is suitable to provide polarity for chemical compatibility, even with corrosive acids and alcohol, but not recommend for acetone, DM, DMSO, base is larger than 6N.
How to maintain the syringe filter?
1. Based on the actual use frequency, periodically remove the filter material in the primary effect syringe filter for cleaning.
2. When it is found that the wind speed becomes low, you should first check whether the surface of the primary air filter is black. If it is black, it means that the pre-filter has more dust holding capacity and the resistance increases. Clean or replace the cloth.
3. When the non-woven fabric is replaced or cleaned, the wind speed cannot be increased, it means that the air filter has been blocked and the resistance has increased, the syringe filter should be replaced.
4. When replacing the syringe filter, the spray ball plate must be removed, the filter should be removed, and the new air filter should be replaced according to the specifications and models of the original syringe filter. When installing, confirm the arrow mark on the syringe filter, and the arrow should point in the direction of the air flow. And make sure the seal is good to prevent leakage.
5.After replacing the syringe filter, make sure that there is no leakage in the frame, and use a dust particle counter to detect it. After the technical indicators are reached, normal operation can be performed.

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